Katuk leaves have been reported by Suprayogi et al. to contain five C17, C18 and C20 polyunsaturated fatty acids and their derivatives (which are significant as precursors in the biosynthesis of eicosanoids such as prostaglandin, prostacycline, thromboxane, lipoxines and leukotrienes), together with a 17-ketosteroid, 3-ethyl-3-hydroxy-5-α-androstran-17-one (possibly involved in the biosynthesis of steroid hormone such as progesterone, estradiol, testosteron and glucocorticoids) and 3,4-dimethyl-2-oxocyclopent-3-enylacetic acid (with likely participation in the citric acid cycle to produce ATP).